Xeomin

Xeomin is a prescription drug and used to treat long-term (chronic) salivation, injected into muscles and is used to:

– treat movement disorders (cervical dystonia and spasticity of the upper limb) in adults

– treat eyelid spasms (blepharospasm) in adults

 

XEOMIN® (incobotulinumtoxinA) for Adults with Upper Limb Spasticity

An estimated 12 million adult patients worldwide suffer from spasticity.

One of the most common causes of spasticity of the upper limb in adults is stroke. After a stroke, signals from the brain to the muscles may not work properly. Signs of spasticity may develop over several weeks or over a longer period of time.

There are other conditions (listed below) that can cause the adult patient’s brain to send the wrong signals to their muscles and cause spasticity of the upper limb.

Other causes of upper limb spasticity in adults include:

– Traumatic brain damage

– Multiple sclerosis

– Problems with the spinal cord

– Cerebral paralysis in adults

The majority of adult patients who were treated with Xeomin with spasticity of the upper limb in clinical trials were adults with spasticity after a stroke.

Treatment

According to the American Academy of Neurology, botulinum toxin injections are the recommended option for the treatment of spasticity of the upper limbs after a stroke.

Symptoms can affect daily activities. The severity of symptoms varies from mild to severe in patients.

 

 

In adults with upper limb spasticity there is an imbalance of signals from the brain to the muscles, which causes stiffness and spasms. This can lead to abnormal arm or hand positions, uncomfortable movement, and pain.

 

 

XEOMIN is injected into muscles to help interfere with these signals. This helps decrease muscle stiffness and improve your ability to function using the affected muscles.

 

 

Some stiffness and spasms may still occur, but less severely.

Xeomin is indicated for the treatment of adults with cervical dystonia.

Cervical dystonia is the most common form of focal dystonia. In adults with cervical dystonia, nerve signals cause the muscles to involuntarily contract. This can lead to incorrect head position, inconvenience of movement and pain.

XEOMIN® (incobotulinumtoxinA) for Adults With Cervical Dystonia

In adults with cervical dystonia, nerve signals tell the muscles to contract when they shouldn’t. This can lead to abnormal head positions, uncomfortable movement, and pain.

 

 

XEOMIN is injected into muscles to help block these signals. This can help decrease muscle activity and neck pain.

 

 

Some muscles may still contract, but less severely.

 

 

XEOMIN® (incobotulinumtoxinA) for Adults With Blepharospasm

In adults with blepharospasm, nerve signals cause the muscles to involuntarily contract. This can cause involuntary movement of the eyelids, which leads to discomfort.

 

 

Symptoms of blepharospasm begin unnoticed and include frequent blinking, tearing, irritation and dry eyes. Symptom progression is common and can lead to severe blindness in serious cases due to the inability to keep eyes open.

In adults with blepharospasm, nerve signals tell the muscles to contract when they should not. This can cause eyelid movement that leads to discomfort.

XEOMIN is injected into muscles to help interfere with these signals. This helps decrease eyelid spasms.

 

 

Some muscles may still contract, but less severely.

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